SCHEMBL22372152

SCHEMBL22372152

O=C(NCC1CC1)c1ncn[nH]1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
SMYD3 Q9H7B4 1/20 0.52
LMNA P02545 2/20 0.51
APOBEC3A P31941 1/20 0.49
APOBEC3G Q9HC16 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
RAB9A P51151 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CCNA2 P20248 1/20 0.41
CDK2 P24941 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365156 0.77 GRIN2B (0.61) SMN1; SMN2CYP2D6RAB9A
SCHEMBL22372185 0.74 MAPK14 (0.49) TDP1
SCHEMBL22372054 0.72 TDP1 (0.40) TDP1KDM4ECCNA2CDK2
SCHEMBL23511762 0.71
SCHEMBL22372222 0.71 L3MBTL1 (0.45) L3MBTL1SMN1; SMN2SMYD3LMNAAPOBEC3A
SCHEMBL22372070 0.71 APOBEC3A (0.68) L3MBTL1SMN1; SMN2SMYD3LMNAAPOBEC3A
SCHEMBL22372145 0.71 AR (0.57) L3MBTL1SMN1; SMN2LMNACYP1A2RAB9A
SCHEMBL4553284 0.69 ROCK2 (0.50) TDP1CCNA2CDK2
SCHEMBL30635495 0.68 NAMPT (0.47) MEN1KMT2ATDP1
SCHEMBL22372067 0.68 TDP1 (0.43) TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 US disclosed
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-06-23 US disclosed
US-11358957-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-06-14 US disclosed
US-20200277287-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2020-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives CYP51A1, MPO, NOX5 L3MBTL1 4183/4885SMN1; SMN2 3586/4885SMYD3 1665/4885
US-20200277287-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG2 L3MBTL1 1061/4885SMN1; SMN2 2990/4885SMYD3 1825/4885
US-11358957-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG2 L3MBTL1 1061/4885SMN1; SMN2 2990/4885SMYD3 1825/4885
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES CYP51A1, MPO, NOX5 L3MBTL1 4183/4885SMN1; SMN2 3586/4885SMYD3 1665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.