SCHEMBL22372189

SCHEMBL22372189

CN(C)CCOC(=O)c1cnc[nH]1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.45
BCHE P06276 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
CHRM1 P11229 5/20 0.41
CHRM2 P08172 4/20 0.41
CHRM4 P08173 4/20 0.41
CHRM5 P08912 4/20 0.41
CHRM3 P20309 4/20 0.41
HRH3 Q9Y5N1 3/20 0.41
HRH4 Q9H3N8 2/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAOA P21397 1/20 0.38
CNR1 P21554 1/20 0.38
DRD4 P21917 1/20 0.38
ACHE P22303 1/20 0.38
HRH2 P25021 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20487937 0.82 ALDH1A1 (0.44) ALDH1A1CHRM1HRH3LMNATP53
SCHEMBL6801136 0.79 LMNA (0.54) HRH3HRH4LMNACYP1A2MAPK1
SCHEMBL1720771 0.78 KDM4E (0.46) ALDH1A1CYP1A2TP53SMN1; SMN2GAA
SCHEMBL22372258 0.75 PHLPP2 (0.45) PHLPP2BCHEALDH1A1MAPTCHRM1
SCHEMBL13531237 0.72 PHLPP2 (0.57) PHLPP2BCHEALDH1A1MAPTCHRM1
SCHEMBL692343 0.72
SCHEMBL22372270 0.72 PHLPP2 (0.49) PHLPP2BCHEALDH1A1MAPTCHRM1
SCHEMBL5140057 0.71 CYP3A4 (0.46) ALDH1A1HRH3HRH4TP53SMN1; SMN2
Hydrochloric Acid SCHEMBL27472182 0.71 TP53 (0.51) ALDH1A1MAPTHRH3CYP1A2MAPK1
Water SCHEMBL5369991 0.71 TP53 (0.51) ALDH1A1HRH3CYP1A2MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 US disclosed
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-06-23 US disclosed
US-11358957-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-06-14 US disclosed
US-20200277287-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2020-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives CYP51A1, MPO, NOX5 PHLPP2 4115/4885BCHE 1997/4885ALDH1A1 258/4885
US-20200277287-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG2 PHLPP2 3292/4885BCHE 1482/4885ALDH1A1 544/4885
US-11358957-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG2 PHLPP2 3292/4885BCHE 1482/4885ALDH1A1 544/4885
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES CYP51A1, MPO, NOX5 PHLPP2 4115/4885BCHE 1997/4885ALDH1A1 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.