Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459763 | 0.90 | ALDH1A1 (0.36) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL26459778 | 0.89 | ALDH1A1 (0.35) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL39951 | 0.89 | APP (0.36) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL29478052 | 0.89 | SMN1; SMN2 (0.37) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL493787 | 0.89 | SMN1; SMN2 (0.37) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL26459779 | 0.88 | ALDH1A1 (0.35) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL26459782 | 0.88 | ALDH1A1 (0.35) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL26459777 | 0.88 | ALDH1A1 (0.36) | GABBR2GABBR1ALDH1A1KDM4EHPGD | |
| SCHEMBL12679255 | 0.87 | MEN1 (0.35) | GABBR2GABBR1ALDH1A1POLBRAB9A | |
| SCHEMBL21183326 | 0.87 | GABBR2 (0.33) | GABBR2GABBR1ALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759780-B2 | Hindered amines | 3V SIGMA S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2020-07-30 | — | — | US | disclosed |
| EP-3424977-B1 | HINDERED POLYMERIC AMINES | 3V SIGMA SPA (IT) | 2020-03-18 | — | — | EP | disclosed |
| EP-3428156-B1 | HINDERED AMINES | 3V SIGMA SPA (IT) | 2020-02-12 | — | — | EP | disclosed |
| US-20190016702-A1 | HINDERED AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-17 | — | — | US | disclosed |
| EP-3428156-A1 | HINDERED AMINES | 3V SIGMA S.p.A (IT) | 2019-01-16 | — | — | EP | disclosed |
| EP-3424977-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.p.A (IT) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002631-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-03 | — | — | US | disclosed |
| EP-2112141-B1 | Oligomeric sterically hindered amines and their use as polymer stabilizers | 3V SIGMA SPA (IT) | 2013-05-15 | — | — | EP | disclosed |
| US-8003718-B2 | Oligomeric sterically hindered amines and their use as polymer stabilisers | 3V SIGMA S.P.A. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | 3V SIGMA S.P.A. (IT) | 2009-10-29 | — | — | US | disclosed |
| EP-2112141-A1 | Oligomeric sterically hindered amines and their use as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | PARG, PARN, PUF60 | GABBR2 3248/4885GABBR1 3080/4885ALDH1A1 884/4885 |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | PCBP1, PARG, PARN | GABBR2 3805/4885GABBR1 3838/4885ALDH1A1 1222/4885 |
| US-20190016702-A1 | HINDERED AMINES | PARG, TAAR5, PARN | GABBR2 2603/4885GABBR1 2263/4885ALDH1A1 638/4885 |
| US-10759780-B2 | Hindered amines | PARG, TAAR5, PARN | GABBR2 2603/4885GABBR1 2263/4885ALDH1A1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.