Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234962 | 0.91 | LTA4H (0.42) | CYP3A4CYP2D6CYP2C9CYP2C19LTA4H | |
| SCHEMBL2237552 | 0.89 | BCHE (0.46) | LTA4HKDM4EBCHEMAOB | |
| SCHEMBL2240254 | 0.88 | KDM4E (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19LTA4H | |
| SCHEMBL2237876 | 0.86 | FUCA1 (0.42) | S1PR5S1PR1KDM4E | |
| SCHEMBL1935382 | 0.86 | S1PR1 (0.42) | S1PR5S1PR1PDCD1CD274 | |
| SCHEMBL2236465 | 0.80 | ALDH1A1 (0.44) | LTA4HPDCD1CD274 | |
| SCHEMBL2238588 | 0.80 | ALDH1A1 (0.44) | CYP2D6KDM4E | |
| SCHEMBL2237326 | 0.78 | ALDH1A1 (0.54) | LTA4H | |
| SCHEMBL2239983 | 0.77 | HDAC1 (0.47) | LTA4HKCNH2KDM4ECHRM2CHRM3 | |
| SCHEMBL2239911 | 0.77 | LTA4H (0.49) | LTA4HMCHR1CD274CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, BRS3 | S1PR5 640/4885S1PR1 381/4885CYP3A4 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.