Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935382 | 0.92 | S1PR1 (0.42) | FUCA1S1PR1S1PR5GBA1ALDH1A1 | |
| SCHEMBL2237424 | 0.86 | S1PR5 (0.40) | S1PR1S1PR5KDM4E | |
| SCHEMBL2236465 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SPHK2SPHK1 | |
| SCHEMBL2238588 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL2237326 | 0.83 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL2239983 | 0.80 | HDAC1 (0.47) | KDM4E | |
| SCHEMBL2234962 | 0.80 | LTA4H (0.42) | KDM4E | |
| SCHEMBL2240254 | 0.80 | KDM4E (0.45) | KDM4E | |
| SCHEMBL2239911 | 0.79 | LTA4H (0.49) | — | |
| SCHEMBL2237552 | 0.79 | BCHE (0.46) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, BRS3 | FUCA1 2616/4885S1PR1 381/4885S1PR5 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.