Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871993 | 0.85 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL6345334 | 0.83 | HTR1A (0.64) | HTR1A | |
| SCHEMBL17063682 | 0.83 | HTR1A (0.63) | HTR1A | |
| SCHEMBL8872125 | 0.82 | HTR1A (0.52) | HTR1ASLC6A4 | |
| SCHEMBL11247527 | 0.82 | HTR6 (0.65) | HTR1A | |
| SCHEMBL8553986 | 0.81 | HTR6 (0.64) | HTR1A | |
| SCHEMBL3094934 | 0.81 | HTR1A (0.68) | HTR1A | |
| SCHEMBL27336161 | 0.80 | HTR1A (0.67) | HTR1A | |
| SCHEMBL15586371 | 0.79 | HTR1A (0.68) | HTR1A | |
| SCHEMBL8558104 | 0.79 | SLC6A4 (0.61) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | HTR1A 4708/4885ACHE 1602/4885SLC6A2 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.