Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557189 | 0.97 | HTR6 (0.64) | HTR6KCNH2HTR1A | |
| SCHEMBL8560281 | 0.90 | SLC6A4 (0.61) | HTR6KCNH2HTR1A | |
| SCHEMBL8558104 | 0.90 | SLC6A4 (0.61) | HTR6KCNH2HTR1A | |
| SCHEMBL11247527 | 0.88 | HTR6 (0.65) | HTR6KCNH2HTR1A | |
| SCHEMBL17063682 | 0.87 | HTR1A (0.63) | HTR1A | |
| SCHEMBL8555865 | 0.87 | HTR7 (0.61) | HTR6KCNH2HTR1A | |
| SCHEMBL8553965 | 0.87 | HTR7 (0.61) | HTR6KCNH2HTR1A | |
| SCHEMBL8878773 | 0.86 | SLC6A4 (0.60) | HTR6KCNH2HTR1A | |
| SCHEMBL8871147 | 0.85 | HTR1A (0.59) | HTR6KCNH2HTR1A | |
| SCHEMBL3094934 | 0.85 | HTR1A (0.68) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683166-B1 | 3-Indolylpiperidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0683166-A1 | 3-Indolylpiperidines | MERCK PATENT GmbH (DE) | 1995-11-22 | — | — | EP | claimed |
| EP-0683166-B1 | 3-Indolylpiperidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0683166-A1 | 3-Indolylpiperidines | MERCK PATENT GmbH (DE) | 1995-11-22 | — | — | EP | disclosed |