Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602061 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10064066 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL354852 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL23494201 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL28783829 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL1906601 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL22374999 | 0.73 | BCHE (0.39) | ALDH1A1 | |
| SCHEMBL19261106 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL19223181 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL16265958 | 0.71 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384094-B2 | Chiral auxiliaries and uses thereof | Greatrex, Ben (AU) | 2022-07-12 | — | — | US | disclosed |
| US-20200270267-A1 | CHIRAL AUXILIARIES AND USES THEREOF | UNIVERSITY OF NEW ENGLAND (AU) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384094-B2 | Chiral auxiliaries and uses thereof | PIN1, CRY1, PIN4 | ALDH1A1 703/4885 |
| US-20200270267-A1 | CHIRAL AUXILIARIES AND USES THEREOF | PIN1, CRY1, PIN4 | ALDH1A1 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.