Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481537 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL1822675 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| Lithium SCHEMBL29773580 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL19100121 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL29714910 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL28348030 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL7635425 | 0.67 | HPRT1 (0.50) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL8516731 | 0.66 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL21326201 | 0.65 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL9681752 | 0.65 | ANPEP (0.42) | KDM4EALDH1A1HSD17B10TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040995-B2 | Catalyst comprising a metallocene complex and co-catalyst | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-06-22 | — | — | US | disclosed |
| US-20200270292-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040995-B2 | Catalyst comprising a metallocene complex and co-catalyst | CCRL2, UBE2L3, MAL2 | KDM4E 1016/4885ALDH1A1 4436/4885HSD17B10 2375/4885 |
| US-20200270292-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST | LAS1L, CCNE2, CKS2 | KDM4E 517/4885ALDH1A1 4402/4885HSD17B10 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.