Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519871 | 0.75 | ALDH1A1 (0.33) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL5136508 | 0.71 | ADRA2A (0.38) | ALDH1A1HPGD | |
| SCHEMBL7571188 | 0.71 | ADRA1D (0.35) | ANPEP | |
| SCHEMBL29481537 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL1822675 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL5859274 | 0.69 | ACHE (0.45) | — | |
| SCHEMBL29714910 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL19100121 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| Lithium SCHEMBL29773580 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL28348030 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861522-A | Production of bridged metallocene complexes and intermediates therefor | ALBEMARLE CORPORATION (US) | 1999-01-19 | — | — | US | claimed |
| US-5710299-A | Production of bridged metallocene complexes and intermediates therefor | ALBEMARLE CORPORATION (US) | 1998-01-20 | — | — | US | claimed |