SCHEMBL20980230

SCHEMBL20980230

CC(C)N[C@@H](CCCCNC(=O)CCCCN=[N+]=[N-])C(=O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 11/20 0.38
▸ HPSE Q9Y251 2/20 0.33
▸ FOLH1 Q04609 2/20 0.33
▸ CNR2 P34972 1/20 0.32
▸ NOD1 Q9Y239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20980231 0.87 ADRB2 (0.32) FOLH1CNR2
SCHEMBL26759938 0.86 GLP1R (0.38) ALBFOLH1
SCHEMBL16248536 0.83 NAMPT (0.40) ALBCNR2NOD1
SCHEMBL21913856 0.82 ALDH1A1 (0.43) ALBFOLH1
SCHEMBL17589403 0.81 LMNA (0.39) ALBCNR2NOD1
SCHEMBL22314737 0.80 ACHE (0.35) —
SCHEMBL25132500 0.80 ALB (0.37) ALBFOLH1NOD1
SCHEMBL25132903 0.80 ALB (0.37) ALBFOLH1NOD1
SCHEMBL25132901 0.80 ALB (0.37) ALBFOLH1NOD1
SCHEMBL14952664 0.79 ALDH1A1 (0.41) ALBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190134214-A1 GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof ASTRAZENECA AB (SE) 2019-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190134214-A1 GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof GLP1R, GIPR, GRPR ALB 4026/4885HPSE 1484/4885FOLH1 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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