SCHEMBL22375470

SCHEMBL22375470

CC(C)C(=O)[C@H](CCCCN=[N+]=[N-])NSS

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.32
▸ CTSL P07711 1/20 0.30
▸ CTSB P07858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24012407 0.82 CNR2 (0.32) CNR2
SCHEMBL20980231 0.81 ADRB2 (0.32) CNR2
SCHEMBL22375471 0.79 FOLH1 (0.32) CNR2
SCHEMBL22375468 0.79 — —
SCHEMBL20980230 0.70 ALB (0.38) CNR2
SCHEMBL24012449 0.70 FOLH1 (0.30) —
SCHEMBL21154982 0.69 ITGB3 (0.32) —
SCHEMBL15706851 0.69 FOLH1 (0.32) CNR2
SCHEMBL14950991 0.69 FOLH1 (0.32) CNR2
SCHEMBL13448062 0.69 FOLH1 (0.39) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200268898-A1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS, INC. 2020-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200268898-A1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF GLP1R, GIPR, GRPR CNR2 1908/4885CTSL 2499/4885CTSB 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback