SCHEMBL22380274

SCHEMBL22380274

C/C(=N\NC(C)(C)C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11492798 1.00 ALDH1A1 (0.32) ALDH1A1KDM4ELMNAGAA
SCHEMBL20214921 1.00 ALDH1A1 (0.32) ALDH1A1KDM4ELMNAGAA
SCHEMBL8781766 0.75
SCHEMBL24198251 0.73
SCHEMBL965841 0.73
Hydrochloric Acid SCHEMBL11683267 0.73
SCHEMBL965842 0.73
SCHEMBL21240996 0.71
SCHEMBL9460482 0.71 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9460484 0.71 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271999-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LIMITED (GB) 2023-08-31 US disclosed
US-20230271999-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LIMITED (GB) 2023-08-31 US disclosed
US-11707531-B2 Compounds, compositions, and methods for the treatment of disease F-star Therapeutics, Inc. (GB) 2023-07-25 US disclosed
US-11707531-B2 Compounds, compositions, and methods for the treatment of disease F-star Therapeutics, Inc. (GB) 2023-07-25 US disclosed
US-20220152215-A1 Immunoconjugates Targeting CEA BOLT BIOTHERAPEUTICS, INC. (US) 2022-05-19 US disclosed
US-20220143012-A1 Macromolecule-Supported TLR Agonists BOLT BIOTHERAPEUTICS, INC. (US) 2022-05-12 US disclosed
US-11160874-B2 Glycoengineered antibody drug conjugates GENZYME CORPORATION (US) 2021-11-02 US disclosed
US-20200268899-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LIMITED (GB) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271999-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE STING1, MAVS, IRF3 ALDH1A1 3301/4885KDM4E 4097/4885LMNA 2679/4885
US-11160874-B2 Glycoengineered antibody drug conjugates CD2BP2, B3GAT3, SIGLEC7 ALDH1A1 3128/4885KDM4E 3676/4885LMNA 4365/4885
US-11707531-B2 Compounds, compositions, and methods for the treatment of disease STING1, MAVS, IRF3 ALDH1A1 3301/4885KDM4E 4097/4885LMNA 2679/4885
US-20200268899-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE STING1, MAVS, IRF3 ALDH1A1 3301/4885KDM4E 4097/4885LMNA 2679/4885
US-20220152215-A1 Immunoconjugates Targeting CEA CD47, FCGR3B, FCGR1A ALDH1A1 1242/4885KDM4E 3982/4885LMNA 4839/4885
US-20220143012-A1 Macromolecule-Supported TLR Agonists TLR8, TLR7, TLR9 ALDH1A1 2748/4885KDM4E 2497/4885LMNA 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.