Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583670 | 0.94 | KDR (0.55) | KDM4ENPC1RAB9ATDO2KDR | |
| SCHEMBL5583581 | 0.88 | KDR (0.49) | NPC1RAB9AKDRPDGFRAMEN1 | |
| SCHEMBL5583672 | 0.88 | SCN9A (0.54) | KDM4ENPC1RAB9AKDRPDGFRA | |
| SCHEMBL5583719 | 0.87 | NPC1 (0.53) | KDM4ENPC1RAB9ATDO2KDR | |
| SCHEMBL5583578 | 0.85 | SMN1; SMN2 (0.53) | NPC1RAB9AKDRMAPTSMN1; SMN2 | |
| SCHEMBL5583655 | 0.85 | RAB9A (0.53) | KDM4ENPC1RAB9AKDRPDGFRA | |
| SCHEMBL5583568 | 0.85 | MEN1 (0.54) | KDM4ENPC1RAB9ATDO2KDR | |
| SCHEMBL5583779 | 0.85 | KDR (0.52) | NPC1RAB9ATDO2KDRPDGFRA | |
| SCHEMBL5583752 | 0.84 | MAPT (0.57) | NPC1RAB9ATDO2KDRMAPT | |
| SCHEMBL5583812 | 0.84 | NPC1 (0.64) | KDM4ENPC1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |