SCHEMBL2238457

SCHEMBL2238457

O=Nc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL11563638 0.86 HTR3E (0.56)
SCHEMBL3284038 0.79 HTR3E (0.58)
SCHEMBL5174355 0.79 HTR3E (0.58)
SCHEMBL9608571 0.75
SCHEMBL2477043 0.75
SCHEMBL2477042 0.75
SCHEMBL130894 0.75
Nitrosobenzene SCHEMBL28051966 0.75 ALDH1A1 (0.46)
SCHEMBL12504044 0.75 KIF11 (0.55)
SCHEMBL472063 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2529388-B1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY MICROMASS LTD (GB) 2019-10-23 EP claimed
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US claimed
US-20130122599-A1 Fragmentation Reagents For Mass Spectrometry MICROMASS UK LIMITED (GB) 2013-05-16 US claimed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US claimed
EP-2529388-A1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY Micromass UK Limited (GB) 2012-12-05 EP claimed
US-8188195-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2012-05-29 US claimed
US-8076479-B2 useful as cyclin-dependent kinase inhibitor compounds; minimizes the need for chromatographic purification of intermediates, and utilizes fewer changes of solvent systems SCHERING CORPORATION (US) 2011-12-13 US claimed
WO-2011092515-A1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY MICROMASS UK LIMITED (GB) 2011-08-04 WO claimed
US-20100168378-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-01 US claimed
EP-2057166-A2 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF (3-ALKYL-5-PIPERIDIN-1-YL-3,3A-DIHYDRO- PYRAZOLOÝ1,5-A¨PYRIMIDIN-7-YL)-AMINO DERIVATIVES AND INTERMEDIATES SCHERING CORPORATION (US) 2009-05-13 EP claimed
WO-2008027220-A2 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF (3-ALKYL-5-PIPERIDIN-1-YL-3, 3A-DIHYDROPYRAZOL0 [1, 5-A] PYRIMIDIN-7-YL) -AMINO DERIVATIVES SCHERING CORPORATION (US) 2008-03-06 WO claimed
US-20080058518-A1 Process and intermediates for the synthesis of (3-alkyl-5-piperidin-1-yl-3,3a-dihydro-pyrazolo[1,5-a]pyrimidin-7-yl)-amino derivatives and intermediates MERCK SHARP & DOHME LLC 2008-03-06 US claimed
EP-0002719-B1 PROCESS FOR THE PREPARATION OF 3-PYRIDAZINONES HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-24 EP claimed
US-4255571-A Catalytic dehydrogenation preparation of 3-pyridazones HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-10 US claimed
EP-0002719-A2 Process for the preparation of 3-pyridazinones HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP claimed
US-20230416815-A1 METHOD FOR LABELING NUCLEIC ACID CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-12-28 US disclosed
EP-4234550-A2 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2023-08-30 EP disclosed
EP-0002719-A2 Process for the preparation of 3-pyridazinones HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed
EP-0002719-A2 Process for the preparation of 3-pyridazinones HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed
US-4025301-A Azo dyes derived from 3-amino pyridine in hair dye compositions SOCIETE ANONYME DITE: L'OREAL (FR) 1977-05-24 US disclosed