SCHEMBL2477043

SCHEMBL2477043

N=Nc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3284038 0.79 HTR3E (0.58)
SCHEMBL5174355 0.79 HTR3E (0.58)
SCHEMBL5317521 0.78 HTR3E (0.47)
SCHEMBL9608571 0.75
SCHEMBL2238457 0.75
SCHEMBL130894 0.75
SCHEMBL2477042 0.75
SCHEMBL22379991 0.75
SCHEMBL27673610 0.75
SCHEMBL670197 0.73 ALDH1A1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696619-B1 Process for dyeing of paper CIBA SC HOLDING AG (CH) 2001-11-14 EP claimed
EP-0601302-B1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes WELLA AG (DE) 1996-07-10 EP claimed
CN-115959997-A Method for reducing nitro-substituted aromatic compound 中国科学院大连化学物理研究所 2023-04-14 CN disclosed
WO-2020236688-A1 NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES, KIDNEY DISEASE AND DIABETES MERCK SHARP & DOHME CORP. (US) 2020-11-26 WO disclosed
WO-2020186220-A1 COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2020-09-17 WO disclosed
US-9999790-B2 2018-06-19 US disclosed
US-20160339274-A1 SYSTEMS FOR CUSTOM COLORATION COLORIGHT LTD. (IL) 2016-11-24 US disclosed
WO-2016127455-A1 PYRIMIDINE DERIVATIVE, CYTOTOXIC AGENT, PHARMACEUTICAL COMPOSITION AND USE THEREOF 南京盖特医药技术有限公司 2016-08-18 WO disclosed
US-9316580-B2 Systems for custom coloration COLORIGHT LTD. (IL) 2016-04-19 US disclosed
EP-2975038-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES Bristol-Myers Squibb Company (US) 2016-01-20 EP disclosed
US-9205283-B2 Systems for custom coloration COLORIGHT LTD. 2015-12-08 US disclosed
EP-1537180-B1 PROCESS FOR PREPARING AZO COMPOUND FUJIFILM CORP (JP) 2011-10-12 EP disclosed
EP-1757660-A1 Cationic mixed dyestuffs comprising an anthraquinone chromophore and their use for hair colouring L'Oréal (FR) 2007-02-28 EP disclosed
EP-1537180-A1 PROCESS FOR PREPARING AZO COMPOUND Fuji Photo Film Co., Ltd. (JP) 2005-06-08 EP disclosed
WO-2004024827-A1 PROCESS FOR PREPARING AZO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-03-25 WO disclosed
EP-0696619-B1 Process for dyeing of paper CIBA SC HOLDING AG (CH) 2001-11-14 EP disclosed
EP-0601302-B1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes WELLA AG (DE) 1996-07-10 EP disclosed
EP-0601302-A1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes Wella Aktiengesellschaft (DE) 1994-06-15 EP disclosed
EP-0601302-A1 Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes Wella Aktiengesellschaft (DE) 1994-06-15 EP disclosed
US-4487719-A Azo dyes from substituted 3-amino-pyridines with aniline, tetrahydroquinoline and benzomorpholine couplers EASTMAN KODAK COMPANY (US) 1984-12-11 US disclosed