Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 6/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364022 | 0.83 | KDM4E (0.41) | KDM4EMAP3K5HDAC3HDAC1HDAC4 | |
| SCHEMBL2240079 | 0.76 | KMT2A (0.48) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4542700 | 0.75 | — | — | |
| SCHEMBL31307605 | 0.74 | KDM4E (0.47) | KDM4EMAP3K5HDAC3HDAC1HDAC4 | |
| SCHEMBL12411796 | 0.74 | KDM4E (0.50) | KDM4EMAP3K5PIM1GRM4GRM5 | |
| SCHEMBL1768624 | 0.73 | KDM4E (0.46) | KDM4EHDAC3HDAC1 | |
| SCHEMBL2238850 | 0.72 | P2RX7 (0.59) | KDM4EGRM4GRM5CTSA | |
| SCHEMBL15997875 | 0.71 | KDM4E (0.44) | KDM4EMAP3K5HDAC3HDAC1HDAC4 | |
| SCHEMBL1768726 | 0.71 | HDAC3 (0.45) | KDM4EMAP3K5HDAC3HDAC1HDAC6 | |
| SCHEMBL2237622 | 0.70 | HSPA9 (0.46) | HDAC3HDAC1GRM5CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531520-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | Polyphor AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011095607-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |