Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA9 | P38646 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364158 | 0.83 | HSPA9 (0.42) | HSPA9ALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL6608254 | 0.77 | CASP3 (0.47) | HSPA9ALDH1A1CASP3CTSAUSP30 | |
| SCHEMBL27699627 | 0.76 | ALDH1A1 (0.50) | HSPA9ALDH1A1PLA2G4ACTSACES1 | |
| SCHEMBL1769145 | 0.76 | GRIN3B (0.48) | HSPA9ALDH1A1 | |
| SCHEMBL1769143 | 0.76 | GRIN3B (0.48) | HSPA9ALDH1A1 | |
| SCHEMBL455410 | 0.75 | — | — | |
| SCHEMBL20712728 | 0.74 | HSPA9 (0.60) | HSPA9ALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL2237713 | 0.72 | RAB9A (0.54) | ALDH1A1HDAC1NPC1RAB9A | |
| SCHEMBL2236830 | 0.71 | HDAC3 (0.45) | HSPA9ALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL1768872 | 0.71 | HDAC3 (0.45) | HSPA9ALDH1A1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531520-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | Polyphor AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011095607-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |