Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238698 | 0.83 | KDM4E (0.46) | KDM4EHDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL2364113 | 0.78 | LONP1 (0.46) | KDM4ELMNA | |
| SCHEMBL2335604 | 0.77 | GABRA5 (0.40) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL2364467 | 0.75 | P2RX7 (0.54) | KDM4EGRM5GRM4LMNAFPR2 | |
| SCHEMBL2073271 | 0.73 | HDAC3 (0.60) | KDM4EHDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL2364158 | 0.73 | HSPA9 (0.42) | HDAC3HDAC1GRM5 | |
| SCHEMBL2364024 | 0.70 | CYP1A2 (0.55) | KDM4EPIM1 | |
| SCHEMBL4542700 | 0.70 | — | — | |
| SCHEMBL2234116 | 0.70 | HDAC3 (0.48) | KDM4EHDAC3HDAC1HDAC6MAP3K5 | |
| SCHEMBL31307605 | 0.70 | KDM4E (0.47) | KDM4EHDAC3HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |