Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413155 | 0.81 | L3MBTL1 (0.55) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22390440 | 0.81 | NTRK1 (0.40) | RIPK1MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10190866 | 0.79 | RIPK1 (0.62) | RIPK1SLC6A2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22957892 | 0.79 | HTT (0.54) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL24180069 | 0.79 | AR (0.47) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28288419 | 0.78 | MAPT (0.52) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1690342 | 0.78 | RIPK1 (0.58) | RIPK1SLC6A2SLC6A4 | |
| SCHEMBL5416008 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL14486495 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7363346 | 0.78 | MAPT (0.46) | SLC6A2SLC6A4MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277296-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277296-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | RIPK1, RIPK4, RIPK3 | RIPK1 1/4885SLC6A2 4695/4885SLC6A4 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.