Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.88 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391548 | 0.97 | RIPK1 (0.88) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL22391510 | 0.94 | RIPK1 (1.00) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22390621 | 0.84 | RIPK1 (0.76) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22391953 | 0.82 | RIPK1 (0.61) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL22957672 | 0.82 | RIPK1 (0.60) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL7318282 | 0.81 | RIPK1 (0.58) | RIPK1HTR2CMCHR1BRD4FAAH | |
| SCHEMBL22957816 | 0.79 | RIPK1 (0.60) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL29786424 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL20472415 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 | |
| SCHEMBL24180094 | 0.78 | RIPK1 (0.55) | RIPK1HTR2CMCHR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277296-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277296-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | RIPK1, RIPK4, RIPK3 | RIPK1 1/4885HTR2C 3194/4885MCHR1 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.