Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22394004 | 0.94 | LMNA (0.34) | LMNAHPGDXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL22394041 | 0.88 | — | — | |
| SCHEMBL20087237 | 0.81 | — | — | |
| SCHEMBL19678654 | 0.80 | — | — | |
| SCHEMBL22394003 | 0.79 | USP2 (0.46) | — | |
| SCHEMBL10000894 | 0.77 | LMNA (0.36) | LMNAHPGDXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL20087224 | 0.76 | — | — | |
| SCHEMBL20087241 | 0.74 | — | — | |
| SCHEMBL20087234 | 0.72 | — | — | |
| SCHEMBL3365694 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814347-B2 | Method for producing fluorinated compounds | MERCK PATENT GMBH (DE) | 2023-11-14 | — | — | US | disclosed |
| US-11814347-B2 | Method for producing fluorinated compounds | MERCK PATENT GMBH (DE) | 2023-11-14 | — | — | US | disclosed |
| US-11247960-B2 | Method for producing fluorinated compounds | MERCK PATENT GMBH (DE) | 2022-02-15 | — | — | US | disclosed |
| US-20200277247-A1 | METHOD FOR PRODUCING FLUORINATED COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247960-B2 | Method for producing fluorinated compounds | FDPS, PFAS, ARFGEF1 | LMNA 1269/4885HPGD 3423/4885XBP1 4407/4885 |
| US-11814347-B2 | Method for producing fluorinated compounds | FDPS, PFAS, ARFGEF1 | LMNA 1269/4885HPGD 3423/4885XBP1 4407/4885 |
| US-20200277247-A1 | METHOD FOR PRODUCING FLUORINATED COMPOUNDS | FDPS, PFAS, ARFGEF1 | LMNA 1269/4885HPGD 3423/4885XBP1 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.