SCHEMBL22394483

SCHEMBL22394483

NCCCCN1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.46
MGLL Q99685 3/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
HEXA P06865 1/20 0.42
HEXB P07686 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
HTR2A P28223 1/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
PIM1 P11309 1/20 0.37
CYP1A2 P05177 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2907080 0.98 FAAH (0.44) FAAHMGLLMEN1KMT2APOLB
SCHEMBL6565273 0.98 FAAH (0.44) FAAHMGLLMEN1KMT2APOLB
SCHEMBL4428365 0.93 MEN1 (0.44) FAAHMGLLMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL12501659 0.91 MEN1 (0.42) FAAHMGLLMEN1KMT2APOLB
SCHEMBL31065451 0.89 MEN1 (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8829446 0.87 FAAH (0.53) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8626070 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8629340 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL8829438 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB
SCHEMBL1982535 0.85 MGLL (0.52) FAAHMGLLMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3962491-B1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES UNIV SANTIAGO COMPOSTELA (ES) 2025-08-06 EP disclosed
US-20220177603-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-06-09 US disclosed
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-03-10 US disclosed
EP-3962491-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES Universidade De Santiago De Compostela (ES) 2022-03-09 EP disclosed
CN-113825515-A Intracellular delivery of anti-KRAS antibodies formulated as nanocapsules 圣地亚哥德孔波斯特拉大学 2021-12-21 CN disclosed
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-07-29 US disclosed
WO-2020221849-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2020-11-05 WO disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN FAAH 2556/4885MGLL 2631/4885MEN1 2022/4885
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN FAAH 2556/4885MGLL 2631/4885MEN1 2022/4885
US-20220177603-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES KRAS, NRAS, TP53 FAAH 4410/4885MGLL 4390/4885MEN1 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.