Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471177 | 0.89 | PTGS1 (0.41) | L3MBTL1MAPTKMT2APTGS1PTGS2 | |
| SCHEMBL30808537 | 0.84 | MAPT (0.41) | DPP4MAPTRAB9ALMNACA12 | |
| SCHEMBL22394632 | 0.84 | MAPT (0.41) | DPP4MAPTRAB9ALMNACA12 | |
| SCHEMBL22394689 | 0.80 | L3MBTL1 (0.42) | L3MBTL1TDP1MAPTRAB9ALMNA | |
| SCHEMBL28465766 | 0.74 | TSHR (0.43) | L3MBTL1RAB9ALMNACA12CA1 | |
| SCHEMBL4630972 | 0.74 | EGFR (0.41) | DPP4MAPTRAB9ALMNACA12 | |
| SCHEMBL28823599 | 0.71 | MAPT (0.60) | MAPTRAB9ALMNACA12CA1 | |
| SCHEMBL22394754 | 0.71 | LMNA (0.52) | L3MBTL1TDP1MAPTRAB9ALMNA | |
| SCHEMBL14341650 | 0.70 | MAPT (0.68) | L3MBTL1TDP1MAPTRAB9ALMNA | |
| SCHEMBL8122012 | 0.69 | EGFR (0.45) | L3MBTL1TDP1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4574153-A2 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | University of Miami (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20250145586-A1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | UNIVERSITY OF MIAMI | 2025-05-08 | — | — | US | disclosed |
| EP-3704103-B1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | UNIV MIAMI (US) | 2025-01-01 | — | — | EP | disclosed |
| US-11926613-B2 | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | UNIVERSITY OF MIAMI (US) | 2024-03-12 | — | — | US | disclosed |
| US-20210163444-A1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | UNIVERSITY OF MIAMI | 2021-06-03 | — | — | US | disclosed |
| EP-3704103-A1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | University of Miami (US) | 2020-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163444-A1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | PNCK, PYGB, PMP22 | DPP4 4150/4885L3MBTL1 2411/4885TDP1 932/4885 |
| US-11926613-B2 | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | PNCK, PYGB, PMP22 | DPP4 4150/4885L3MBTL1 2411/4885TDP1 932/4885 |
| US-20250145586-A1 | KINASE INHIBITORS FOR THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS | MAP3K20, MAP4K2, MAP4K1 | DPP4 3665/4885L3MBTL1 1469/4885TDP1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.