Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21199085 | 1.00 | CNR1 (0.44) | CNR1CNR2RORCHDAC2KDM1A | |
| SCHEMBL5672765 | 0.85 | KDM1A (0.48) | CNR1CNR2RORCHDAC2KDM1A | |
| SCHEMBL7825970 | 0.82 | LMNA (0.46) | CNR1CNR2POLB | |
| SCHEMBL2798515 | 0.81 | CYP3A4 (0.50) | KDM1AHDAC1KMT2A | |
| SCHEMBL2993411 | 0.81 | OPRD1 (0.48) | RORCUSP30 | |
| SCHEMBL2798512 | 0.81 | HDAC2 (0.47) | CNR1CNR2RORCHDAC2KDM1A | |
| SCHEMBL21199360 | 0.81 | KDM1A (0.40) | CNR1CNR2RORCHDAC2KDM1A | |
| SCHEMBL21199358 | 0.80 | RORC (0.48) | RORCHDAC2KDM1AHDAC1KMT2A | |
| SCHEMBL14357682 | 0.78 | KDM1A (0.48) | CNR1CNR2RORCHDAC2KDM1A | |
| SCHEMBL13183437 | 0.78 | OPRD1 (0.46) | RORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2020-09-09 | — | — | EP | disclosed |