Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045748 | 1.00 | LMNA (0.54) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL14518378 | 0.94 | LMNA (0.52) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL8812353 | 0.91 | LMNA (0.54) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL329052 | 0.91 | APP (0.46) | LMNABLMMEN1KMT2AAPP | |
| SCHEMBL966471 | 0.89 | APP (0.44) | LMNABLMAPPPTGS1PDE4A | |
| SCHEMBL28621315 | 0.89 | APP (0.44) | LMNABLMAPPPTGS1PDE4A | |
| Ammonia Solution, Strong SCHEMBL18008289 | 0.89 | APP (0.44) | LMNABLMAPPPTGS1PDE4A | |
| SCHEMBL14915359 | 0.86 | APP (0.42) | LMNABLMAPPPTGS1PDE4A | |
| SCHEMBL16308960 | 0.86 | APP (0.42) | LMNABLMAPPPTGS1PDE4A | |
| SCHEMBL28530390 | 0.86 | APP (0.42) | LMNABLMAPPPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012799-B1 | METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES | CHIMERIX INC (US) | 2016-08-24 | — | — | EP | disclosed |
| US-8299308-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8232432-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-8044249-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| US-7994369-B2 | Specific polybranched polyaldehydes, polyalcohols, and surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994143-B2 | Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates | CHIMERIX, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20100249056-A1 | Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates | CHIMERIX, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-7749983-B2 | Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates | CHIMERIX, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20100137649-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | THE PROCTER & GAMBLE COMPANY | 2010-06-03 | — | — | US | disclosed |
| US-20100105958-A1 | Specific Polybranched Polyaldehydes, Polyalcohols, and Surfactants, and Consumer Products Based Thereon | THE PROCTER & GAMBLE COMPANY | 2010-04-29 | — | — | US | disclosed |
| EP-2012799-A2 | METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES | Chimerix, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20080009462-A1 | Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates | CHIMERIX, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| WO-2007130783-A2 | METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES | CHIMERIX, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137649-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885PTPN1 4053/4885 |
| US-20100249056-A1 | Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates | PNP, TYMP, ENPP1 | LMNA 3293/4885BLM 1945/4885PTPN1 741/4885 |
| US-20100105958-A1 | Specific Polybranched Polyaldehydes, Polyalcohols, and Surfactants, and Consumer Products Based Thereon | ADH1C, ADH1A, ADH5 | LMNA 1144/4885BLM 1818/4885PTPN1 4776/4885 |
| US-20080009462-A1 | Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates | PNP, TYMP, ENPP1 | LMNA 3293/4885BLM 1945/4885PTPN1 741/4885 |
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885PTPN1 4053/4885 |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885PTPN1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.