SCHEMBL22407046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28391562	0.88	CES2 (0.53)	ARCES2TLR8MEN1KMT2A
	SCHEMBL22406885	0.87	AR (0.47)	ARMAPK10TLR8FLT1FLT4
	SCHEMBL28391171	0.87	CES2 (0.41)	CES2TLR8HTR2ASLC6A4KCNH2
	SCHEMBL28391315	0.87	CES2 (0.41)	ARMAPK10CES2MEN1KMT2A
	SCHEMBL28665319	0.86	AR (0.51)	ARMAPK10TLR8FLT1FLT4
	SCHEMBL22439725	0.85	AR (0.52)	ARMAPK10CES2TLR8FLT1
	SCHEMBL14645660	0.83	AR (0.54)	ARMAPK10TLR8FLT1FLT4
	SCHEMBL29741809	0.83	AR (0.54)	ARMAPK10TLR8FLT1FLT4
	SCHEMBL29093106	0.83	AR (0.56)	ARTLR8FLT1FLT4KDR
	SCHEMBL22406928	0.82	CYP11B1 (0.48)	TLR8KMT2ABRAFHDAC1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.