SCHEMBL22409050

SCHEMBL22409050

c1ccc2cc(-c3ccc(-c4cc5c6ccncc6c(-c6ccc(-c7ccc8ccccc8c7)cc6)cc5c5ccccc45)cc3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.53
CYP17A1 P05093 1/20 0.53
CYP19A1 P11511 1/20 0.53
CYP11B2 P19099 1/20 0.53
MAPK9 P45984 3/20 0.47
MAPK10 P53779 3/20 0.47
MAPK8 P45983 2/20 0.47
TDO2 P48775 2/20 0.45
PRKCZ Q05513 1/20 0.44
TNF P01375 1/20 0.44
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CCNC P24863 5/20 0.42
CDK8 P49336 5/20 0.42
HTR2B P41595 1/20 0.42
HTR5A P47898 1/20 0.42
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.41
RAD52 P43351 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27330145 0.89 CYP11B1 (0.46) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL18541150 0.85 ESR1 (0.55) CYP11B1CYP17A1CYP19A1CYP11B2ESR1
SCHEMBL1102697 0.81 CYP11B2 (0.56) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL26833641 0.81 CYP11B1 (0.47) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL1102710 0.80 CYP11B1 (0.54) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL27340445 0.80 CYP11B1 (0.45) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL1102950 0.80 CYP11B2 (0.57) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL1102717 0.80 CYP11B2 (0.57) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL1102750 0.79 CYP11B2 (0.57) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9
SCHEMBL17692306 0.79 TDO2 (0.58) CYP11B1CYP17A1CYP19A1CYP11B2MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325932-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-10 US disclosed
US-20200283462-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION, 2020-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283462-A1 Organic Electroluminescent Materials and Devices L1CAM, KCNN4, ITGB4 CYP11B1 3337/4885CYP17A1 3782/4885CYP19A1 3047/4885
US-11325932-B2 Organic electroluminescent materials and devices L1CAM, RTN4, KCNN4 CYP11B1 2924/4885CYP17A1 3442/4885CYP19A1 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.