Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.39 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944501 | 0.97 | SCN1A (0.45) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL28431629 | 0.94 | SCN1A (0.43) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL20464890 | 0.81 | MEN1 (0.43) | SCN1ASCN2ASCN3AACHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9788455 | 0.79 | SCN1A (0.41) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL3696758 | 0.76 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL28761585 | 0.76 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL1149415 | 0.76 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL3686620 | 0.76 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL25725438 | 0.76 | BBOX1 (0.35) | — | |
| SCHEMBL5944590 | 0.74 | DNM1 (0.37) | CHRNA7CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512268-B2 | Storage-stable enzyme preparations, their production and use | BASF SE (DE) | 2022-11-29 | — | — | US | disclosed |
| US-20210071118-A1 | COMPOSITIONS, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2021-03-11 | — | — | US | disclosed |
| WO-2020229480-A1 | COMPOUNDS STABILIZING HYDROLASES IN LIQUIDS | BASF SE (DE) | 2020-11-19 | — | — | WO | disclosed |
| EP-3717611-A1 | COMPOSITIONS, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2020-10-07 | — | — | EP | disclosed |
| EP-3717612-A1 | STORAGE-STABLE ENZYME PREPARATIONS, THEIR PRODUCTION AND USE | BASF SE (DE) | 2020-10-07 | — | — | EP | disclosed |
| US-20200291334-A1 | STORAGE-STABLE ENZYME PREPARATIONS, THEIR PRODUCTION AND USE | BASF SE (DE) | 2020-09-17 | — | — | US | disclosed |
| CN-111417707-A | Storage-stable enzyme preparations, their production and use | 巴斯夫欧洲公司 | 2020-07-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512268-B2 | Storage-stable enzyme preparations, their production and use | NCEH1, BCHE, APEH | CHRM1 217/4885CHRM3 270/4885CHRM2 227/4885 |
| US-20200291334-A1 | STORAGE-STABLE ENZYME PREPARATIONS, THEIR PRODUCTION AND USE | NCEH1, BCHE, APEH | CHRM1 223/4885CHRM3 264/4885CHRM2 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.