Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.38 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.37 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22409396 | 0.79 | SCN1A (0.43) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL7866802 | 0.76 | SCN1A (0.38) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL5944501 | 0.76 | SCN1A (0.45) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL8057836 | 0.74 | ALDH1A1 (0.36) | LMNATSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28431629 | 0.74 | SCN1A (0.43) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL1149415 | 0.72 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL3686620 | 0.72 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL3696758 | 0.72 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| SCHEMBL28761585 | 0.72 | SCN1A (0.42) | SCN1ASCN2ASCN3ACHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL29067668 | 0.72 | CHRM1 (0.45) | SCN1ASCN2ASCN3ACHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043007-A | Process for the production of fertilizer and the fertilizer produced thereby | DAVIS BOBBY G (US) | 1991-08-27 | — | — | US | claimed |
| US-5043007-A | Process for the production of fertilizer and the fertilizer produced thereby | DAVIS BOBBY G (US) | 1991-08-27 | — | — | US | disclosed |