SCHEMBL22409672

SCHEMBL22409672

c1ccc(-c2nccc3c2oc2ccc(-n4c5ccccc5c5ccccc54)cc23)c(-c2ccccc2-c2nccc3c2sc2ccccc23)c1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.31
PIK3CA P42336 2/20 0.31
PIK3CD O00329 2/20 0.31
PIK3CB P42338 2/20 0.31
BRD4 O60885 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22410585 0.87 MAPT (0.37) PRKDC
SCHEMBL22409562 0.87 ALOX5 (0.34)
SCHEMBL22409579 0.84 ALOX5 (0.37) PRKDCPIK3CAPIK3CDPIK3CBBRD4
SCHEMBL22409671 0.83 ALOX5 (0.34) PRKDCPIK3CAPIK3CDPIK3CBBRD4
SCHEMBL22409544 0.82 ALOX5 (0.33) PRKDC
SCHEMBL21147912 0.81 PRKDC (0.45) PRKDCPIK3CAPIK3CDPIK3CBBRD4
SCHEMBL21914262 0.80 PRKDC (0.44) PRKDCPIK3CAPIK3CDPIK3CBBRD4
SCHEMBL21914403 0.80 PRKDC (0.44) PRKDCPIK3CAPIK3CDPIK3CBBRD4
SCHEMBL25638823 0.79 ALOX5 (0.33) PRKDC
SCHEMBL23433203 0.78 PRKDC (0.45) PRKDCPIK3CAPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200283450-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2020-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283450-A1 Organic electroluminescent materials and devices RPS4X, RPS4Y1, SPIN4 PRKDC 2884/4885PIK3CA 2690/4885PIK3CD 3504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.