SCHEMBL22409671

SCHEMBL22409671

c1ccc(-c2nccc3c2oc2ccccc23)c(-c2ccccc2-c2nccc3c2sc2ccccc23)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.34
MAPT P10636 3/20 0.34
NPC1 O15118 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
PRKDC P78527 3/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
LIMK1 P53667 2/20 0.33
ESR2 Q92731 2/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22409673 0.94 ALOX5 (0.41) ALOX5MAPTNPC1PRKDCPIK3CD
SCHEMBL11941245 0.86 MAPT (0.35) MAPTNPC1SMN1; SMN2LMNAKMT2A
SCHEMBL22410587 0.85 SMN1; SMN2 (0.44) ALOX5MAPTNPC1SMN1; SMN2LMNA
SCHEMBL22409564 0.85 GPR3 (0.43) ALOX5MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL22409666 0.85 PRKDC (0.37) ALOX5MAPTLMNAKMT2AMEN1
SCHEMBL18090103 0.83 PRKDC (0.34) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18090091 0.83 PRKDC (0.34) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18090104 0.83 PRKDC (0.32) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL22409672 0.83 PRKDC (0.31) PRKDCPIK3CDPIK3CBBRD4PIK3CA
SCHEMBL11941252 0.82 MEN1 (0.33) ALOX5MAPTNPC1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200283450-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2020-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283450-A1 Organic electroluminescent materials and devices RPS4X, RPS4Y1, SPIN4 ALOX5 3170/4885MAPT 4859/4885NPC1 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.