Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677879 | 0.89 | SLC6A4 (0.67) | SLC6A4HSD17B10SMN1; SMN2USP2TP53 | |
| SCHEMBL7294320 | 0.82 | HTR4 (0.62) | SLC6A4NPSR1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL18413857 | 0.82 | SLC6A4 (0.56) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E | |
| SCHEMBL24445505 | 0.81 | HSD17B10 (0.56) | SLC6A4HSD17B10SMN1; SMN2USP2TP53 | |
| SCHEMBL18395931 | 0.81 | SLC6A4 (0.55) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E | |
| SCHEMBL20149705 | 0.81 | SLC6A4 (0.55) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E | |
| Hydrochloric Acid SCHEMBL18395437 | 0.80 | SLC6A4 (0.56) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E | |
| SCHEMBL18413804 | 0.79 | HSD17B10 (0.59) | HSD17B10SMN1; SMN2USP2TP53KDM4E | |
| Sulfuric Acid SCHEMBL22393226 | 0.78 | SLC6A4 (0.51) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E | |
| Sulfuric Acid SCHEMBL22393227 | 0.78 | SLC6A4 (0.51) | SLC6A4HSD17B10SMN1; SMN2USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324958-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2021-07-28 | — | — | EP | disclosed |
| US-20200283385-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA, INC. | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283385-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | IDO1, IDO2, INMT | SLC6A4 21/4885HSD17B10 2226/4885SMN1; SMN2 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.