Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066614 | 0.86 | FFAR1 (0.70) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL3501067 | 0.85 | NR4A2 (0.64) | NR4A2FFAR1MAOBPARP10HRH3 | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.84 | FFAR1 (0.68) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| Hydrochloric Acid SCHEMBL10622121 | 0.84 | FFAR1 (0.68) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL3054083 | 0.84 | PLA2G4B (0.64) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL4222632 | 0.84 | FFAR1 (0.68) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| Benzylphenylether SCHEMBL27549280 | 0.83 | NR4A2 (0.67) | NR4A1NR4A2NR4A3FFAR1FFAR4 | |
| SCHEMBL1796796 | 0.83 | FFAR1 (0.77) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL2790268 | 0.83 | NR4A2 (0.62) | NR4A2FFAR1MAOBLTB4RLTB4R2 | |
| SCHEMBL6169826 | 0.83 | ALOX5 (0.61) | ALOX5NR4A1NR4A2NR4A3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101613335-B | Natural product 5,7-dimethoxy-4'-hydroxyisoflavone preparation method | UNIV DONGHUA | 2011-07-20 | — | — | CN | claimed |
| CN-101613335-A | Natural product 5, the preparation method of 7-dimethoxy-4 ' ＇-hydroxy-isoflavone | UNIV DONGHUA | 2009-12-30 | — | — | CN | claimed |
| US-20240408092-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | UNIV CASE WESTERN RESERVE (US) | 2024-12-12 | — | — | US | disclosed |
| CN-115536584-B | Synthesis method of norlinderane hydrochloride | 珠海润都制药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-11944624-B2 | Peptide and small molecule agonists of EphA and their uses | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-04-02 | — | — | US | disclosed |
| CN-112521395-B | Preparation method of galanthamine | 鲁南制药集团股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115536584-A | Synthetic method of higenamine hydrochloride | 珠海润都制药股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-112521395-A | Preparation method of galanthamine | 鲁南制药集团股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-20200222405-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | CASE WESTERN RESERVE UNIVERSITY | 2020-07-16 | — | — | US | disclosed |
| US-20200222405-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | CASE WESTERN RESERVE UNIVERSITY | 2020-07-16 | — | — | US | disclosed |
| EP-3648766-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | Case Western Reserve University (US) | 2020-05-13 | — | — | EP | disclosed |
| US-4733000-A | OLIGOPEPTIDES FOR HYPOTENSIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4681879-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4608374-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0061172-B1 | PHOSPHORUS-CONTAINING OLIGOPEPTIDES, PROCESSES FOR PREPARATION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4421763-A | HYPOTENSIVE AGENTS | EISAI CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0061172-A1 | Phosphorus-containing oligopeptides, processes for preparation thereof and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-09-29 | — | — | EP | disclosed |
| US-4350705-A | HYPOTENSIVE AGENTS | EISAI CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| EP-0017195-A1 | Derivatives of 2,5-disubstituted-cyclohexane-1,3-diones, process for preparation thereof and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222405-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | EPHA1, EPHA7, EPHA3 | ALOX5 2693/4885NR4A1 1465/4885NR4A2 1483/4885 |
| US-11944624-B2 | Peptide and small molecule agonists of EphA and their uses | EPHA1, EPHA7, EPHA3 | ALOX5 2693/4885NR4A1 1465/4885NR4A2 1483/4885 |
| US-20240408092-A1 | PEPTIDE AND SMALL MOLECULE AGONISTS OF EPHA AND THEIR USES | EPHA1, EPHA7, EPHA3 | ALOX5 2693/4885NR4A1 1465/4885NR4A2 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.