Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208242 | 0.85 | ALOX5 (0.59) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL2166377 | 0.83 | ALOX5 (0.65) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL224149 | 0.83 | ALOX5 (0.65) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL12963330 | 0.83 | LMNA (0.63) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL1066614 | 0.83 | FFAR1 (0.70) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL5300752 | 0.83 | ALOX5 (0.61) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL41907 | 0.82 | CES1 (0.58) | LMNAPTGS1HDAC6L3MBTL1 | |
| SCHEMBL4222632 | 0.81 | FFAR1 (0.68) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.81 | FFAR1 (0.68) | ALOX5NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL8694782 | 0.81 | SRD5A2 (0.58) | FFAR1FFAR4PPARGPPARASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888341-B1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | AVENTIS PHARMA SA (FR) | 2005-11-30 | — | — | EP | disclosed |
| EP-0361365-A1 | Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use | E.R. SQUIBB & SONS, INC. (US) | 1990-04-04 | — | — | EP | disclosed |