SCHEMBL224165

SCHEMBL224165

COC(=O)c1ccc(N)cc1OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
GAA P10253 6/20 0.66
KDM4E B2RXH2 4/20 0.58
POLB P06746 1/20 0.53
MAPT P10636 4/20 0.51
HSD17B10 Q99714 3/20 0.51
HPGD P15428 2/20 0.51
GLA P06280 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
ATM Q13315 1/20 0.51
ABL1 P00519 1/20 0.50
CRBN Q96SW2 1/20 0.48
CFTR P13569 2/20 0.47
TSHR P16473 2/20 0.47
HTT P42858 2/20 0.47
MAPK1 P28482 1/20 0.47
HTR4 Q13639 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7410231 0.98 ALDH1A1 (0.69) ALDH1A1GAAKDM4EPOLBMAPT
Potassium Ion SCHEMBL28870541 0.96 ALDH1A1 (0.67) ALDH1A1GAAKDM4EPOLBMAPT
SCHEMBL31321291 0.90 GAA (0.58) ALDH1A1GAAKDM4EPOLBMAPT
SCHEMBL1761307 0.86 ALDH1A1 (0.54) ALDH1A1GAAKDM4EPOLBMAPT
SCHEMBL570110 0.85 GAA (0.61) ALDH1A1GAAKDM4EPOLBMAPT
SCHEMBL8000660 0.85 ALDH1A1 (0.76) ALDH1A1GAAKDM4EMAPTHSD17B10
SCHEMBL15055753 0.84 GAA (0.60) ALDH1A1GAAKDM4EPOLBMAPT
Hydrochloric Acid SCHEMBL15488205 0.84 GAA (0.59) ALDH1A1GAAKDM4EPOLBMAPT
Hydrochloric Acid SCHEMBL7564049 0.84 GAA (0.59) ALDH1A1GAAKDM4EPOLBMAPT
SCHEMBL8718148 0.83 ALDH1A1 (0.51) ALDH1A1GAAKDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 987 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118993910-B Preparation method of 2-methoxy-4-aminobenzoic acid methyl ester 山东佰隆医药有限公司 2025-03-14 CN claimed
CN-118993910-A Preparation method of 2-methoxy-4-aminobenzoic acid methyl ester 山东佰隆医药有限公司 2024-11-22 CN claimed
CN-117447338-B Lenvatinib intermediate Synthesis method of intermediate 南昌大学第二附属医院 2024-11-15 CN claimed
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
CN-117447338-A Synthesis method of lenvatinib intermediate 南昌大学第二附属医院 2024-01-26 CN claimed
CN-117417282-A Preparation method of amisulpride intermediate and preparation process of amisulpride 常州康普药业有限公司 2024-01-19 CN claimed
CN-117185969-A Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid 江苏阿尔法药业股份有限公司 2023-12-08 CN claimed
CN-216877922-U Cooling crystallization device for preparing 2-methoxy-4-methyl aminobenzoate 济南泺合医药技术有限公司 2022-07-05 CN claimed
CN-114230497-A Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid 广东省科学院生物与医学工程研究所 2022-03-25 CN claimed
US-10696611-B2 Adamantane derivative compound AMOREPACIFIC CORPORATION (KR) 2020-06-30 US claimed
CN-111138307-A Aryl halide and synthesis method and application thereof 华东师范大学 2020-05-12 CN claimed
CN-109456267-A A method of synthesis pleasure is cut down for Buddhist nun 南京天越星生物技术有限公司 2019-03-12 CN claimed
CN-105237422-A Synthetic method of 4-amino-5-chloro-2-methoxyl benzoic acid UNIV NANJING SCIENCE & TECH 2016-01-13 CN claimed
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 EP disclosed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 WO disclosed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
EP-0067615-A1 Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions BEECHAM GROUP PLC (GB) 1982-12-22 EP disclosed
EP-0055524-A2 Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1982-07-07 EP disclosed
EP-0042705-A1 Azabicycloalkane derivatives, their preparation and use BEECHAM GROUP PLC (GB) 1981-12-30 EP disclosed
US-4039672-A EMESIS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696611-B2 Adamantane derivative compound ADAM8, BACE1, CYP17A1 ALDH1A1 194/4885GAA 743/4885KDM4E 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.