Sugi Predict

Sugi Predict / Compounds / SCHEMBL570110

SCHEMBL570110

SCHEMBL570110

COC(=O)c1cc(N)ccc1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 5/20 0.61
▸ KDM4E B2RXH2 7/20 0.58
▸ ALDH1A1 P00352 7/20 0.56
▸ POLB P06746 1/20 0.53
▸ MAPT P10636 5/20 0.47
▸ HSD17B10 Q99714 4/20 0.47
▸ HPGD P15428 4/20 0.47
▸ GLA P06280 1/20 0.47
▸ CASP1 P29466 1/20 0.47
▸ CASP7 P55210 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ CFTR P13569 1/20 0.47
▸ ABL1 P00519 1/20 0.46
▸ EGFR P00533 1/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ TSHR P16473 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ LMNA P02545 2/20 0.45
▸ ALOX15 P16050 1/20 0.45
▸ HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7564049 0.98 GAA (0.59) GAAKDM4EALDH1A1POLBMAPT
Hydrochloric Acid SCHEMBL15488205 0.98 GAA (0.59) GAAKDM4EALDH1A1POLBMAPT
SCHEMBL26265451 0.86 GAA (0.57) GAAKDM4EALDH1A1POLBMAPT
SCHEMBL224165 0.85 ALDH1A1 (0.71) GAAKDM4EALDH1A1POLBMAPT
SCHEMBL5317567 0.84 GAA (0.56) GAAKDM4EALDH1A1POLBMAPT
SCHEMBL6589289 0.84 GAA (0.51) GAAKDM4EALDH1A1POLBHPGD
Hydrochloric Acid SCHEMBL7410231 0.84 ALDH1A1 (0.69) GAAKDM4EALDH1A1POLBMAPT
SCHEMBL31295589 0.83 ALDH1A1 (0.58) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL623759 0.83 ALDH1A1 (0.58) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL98371 0.83 ALDH1A1 (0.73) GAAKDM4EALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144743-A1 COMPOUNDS TMEM16A LIMITED (GB) 2026-05-28 — — US disclosed
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-21 — — US disclosed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 — — WO disclosed
EP-4699655-A2 COMPOUNDS TMEM16A LIMITED (GB) 2026-02-25 — — EP disclosed
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2026-01-22 — — US disclosed
EP-4647127-A2 COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS Exelixis, Inc. (US) 2025-11-12 — — EP disclosed
US-20250268903-A1 RXFP1 AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-08-28 — — US disclosed
US-12377105-B2 Compounds TMEM16A LIMITED (GB) 2025-08-05 — — US disclosed
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2025-07-29 — — US disclosed
EP-3743070-B1 COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS EXELIXIS INC (US) 2025-07-23 — — EP disclosed
WO-1997019074-A1 SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES HOECHST MARION ROUSSEL, INC. (US) 1997-05-29 — — WO disclosed
EP-0675886-A1 AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1995-10-11 — — EP disclosed
US-5382590-A Gastrointestinal disorders and nervous system disorders RHONE-POULENC RORER S.A. (FR) 1995-01-17 — — US disclosed
WO-1994013663-A1 AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1994-06-23 — — WO disclosed
US-4431663-A ANTIULCER AND NEUROLEPTIC AGENTS; ANTIEMETICS SHIONOGI & CO., LTD. (JP) 1984-02-14 — — US disclosed
US-4351770-A Preparation of N(2-pyrrolidinylmethyl)2-methoxy-5-benzenesulfonamidobenzamides SHIONOGI & CO., LTD. (JP) 1982-09-28 — — US disclosed
US-4350635-A ANTIEMETICS, NEUROLEPTIC AGENTS SHIONOGI & CO., LTD. (JP) 1982-09-21 — — US disclosed
US-4330472-A Meta-sulfonamido-benzamide derivatives SHIONOGI & CO., LTD. (JP) 1982-05-18 — — US disclosed
US-4328155-A ANTIEMETIC OR PSYCHOTROPIC AGENT SHIONOGI & CO., LTD. (JP) 1982-05-04 — — US disclosed
US-4328344-A ANTIEMETIC SHIONOGI & CO., LTD. (JP) 1982-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144743-A1 COMPOUNDS CACNA1E, TMEM109, CACNA1C GAA 1568/4885KDM4E 3794/4885ALDH1A1 1592/4885
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF CASP1, CASP3, BAD GAA 3520/4885KDM4E 3961/4885ALDH1A1 1186/4885
US-20250268903-A1 RXFP1 AGONISTS RXFP1, RXFP2, RXFP3 GAA 2587/4885KDM4E 3426/4885ALDH1A1 1820/4885
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 GAA 1597/4885KDM4E 2343/4885ALDH1A1 602/4885
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, NR1H4, CNR1 GAA 3845/4885KDM4E 2121/4885ALDH1A1 807/4885
US-12377105-B2 Compounds CACNA1E, TMEM109, CACNA1A GAA 1147/4885KDM4E 3113/4885ALDH1A1 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.