Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | EIF2AK3 | Q9NZJ5 | 16/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.42 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NEK4 | P51957 | 1/20 | 0.42 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633632 | 0.85 | EIF2AK3 (0.51) | FLT3EIF2AK3RET | |
| SCHEMBL22418477 | 0.80 | TEK (0.52) | FLT3AXLMETEIF2AK3LCK | |
| SCHEMBL30569254 | 0.77 | LCK (0.42) | FLT3LCK | |
| SCHEMBL30441772 | 0.75 | RET (0.47) | FLT3RET | |
| SCHEMBL22418463 | 0.73 | FLT3 (0.52) | FLT3AXLMETLCK | |
| SCHEMBL31264664 | 0.73 | EIF2AK3 (0.50) | AXLMETEIF2AK3RIPK1 | |
| SCHEMBL31264760 | 0.73 | EIF2AK3 (0.50) | AXLMETEIF2AK3RIPK1 | |
| SCHEMBL20351725 | 0.72 | MET (0.48) | FLT3AXLMETEIF2AK3LCK | |
| SCHEMBL28772346 | 0.72 | EIF2AK3 (0.44) | FLT3AXLMETEIF2AK3RIPK1 | |
| SCHEMBL20351744 | 0.72 | SRC (0.57) | EIF2AK3LCKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689991-B | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2023-06-09 | — | — | CN | disclosed |