Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302434 | 0.95 | THRB (0.35) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22361793 | 0.94 | FFAR1 (0.35) | NPC1MAPTKMT2ASMN1; SMN2THRB | |
| SCHEMBL19295711 | 0.91 | NPC1 (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19295737 | 0.91 | NPC1 (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22361660 | 0.91 | FFAR1 (0.35) | NPC1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15356545 | 0.89 | THRB (0.39) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21793389 | 0.88 | THRB (0.35) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19295720 | 0.88 | THRB (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14826285 | 0.88 | THRB (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22361792 | 0.87 | ENPP2 (0.35) | NPC1MAPTTHRBGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774212-B2 | Thermally conductive material, resin composition, and device | FUJIFILM CORPORATION (JP) | 2020-09-15 | — | — | US | disclosed |