Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 9/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20939798 | 0.76 | MAP3K14 (0.34) | MAP3K14 | |
| SCHEMBL22421129 | 0.75 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL22421146 | 0.75 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL22421148 | 0.72 | ALDH1A1 (0.33) | MAP3K14 | |
| SCHEMBL20939184 | 0.68 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL22421168 | 0.68 | NPC1 (0.54) | MAP3K14KAT2B | |
| SCHEMBL20939543 | 0.67 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL23005491 | 0.65 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL22421103 | 0.65 | PRMT5 (0.39) | MAP3K14KAT2B | |
| SCHEMBL24026521 | 0.64 | CACNA2D1 (0.36) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478673-B1 | CYANOINDOLINE DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-09-16 | — | — | EP | disclosed |