Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22423516 | 0.92 | GLP1R (0.54) | GLP1RNOD1CASP2FAAHSLC6A5 | |
| SCHEMBL21389124 | 0.90 | CASP2 (0.51) | NOD1CASP2TLR2FAAHSLC6A5 | |
| SCHEMBL45887 | 0.84 | GLP1R (0.57) | GLP1RNOD1CASP2TLR2SIRT2 | |
| SCHEMBL23544195 | 0.84 | GLP1R (0.61) | GLP1RNOD1 | |
| SCHEMBL23552373 | 0.84 | GLP1R (0.51) | GLP1RNOD1CASP2FAAHSIRT2 | |
| SCHEMBL22423517 | 0.83 | GLP1R (0.49) | GLP1REPHX2 | |
| SCHEMBL25944773 | 0.83 | GLP1R (0.37) | GLP1R | |
| SCHEMBL45885 | 0.83 | GLP1R (0.56) | GLP1RNOD1TLR2SIRT2EPHX2 | |
| SCHEMBL16525843 | 0.83 | GLP1R (0.56) | GLP1RNOD1TLR2SIRT2EPHX2 | |
| SCHEMBL23544191 | 0.82 | GLP1R (0.55) | GLP1RNOD1CASP2FAAHSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447067-B1 | GLP-1R/GCGR DUAL TARGET AGONIST POLYPEPTIDE FOR TREATING NON-ALCOHOLIC FATTY LIVER DISEASES | SHENZHEN TURIER BIOTECH CO LTD (CN) | 2021-06-23 | — | — | EP | disclosed |