Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 6/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389124 | 0.90 | CASP2 (0.51) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL22423516 | 0.89 | GLP1R (0.54) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL21389120 | 0.89 | NOD1 (0.63) | NOD1EPHX2SLC6A5GLP1R | |
| SCHEMBL24796610 | 0.89 | NOD1 (0.58) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL20016978 | 0.88 | CASP2 (0.51) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL24155207 | 0.86 | CASP2 (0.56) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL15759326 | 0.86 | CASP2 (0.56) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL24483387 | 0.86 | CASP2 (0.56) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL16221915 | 0.86 | CASP2 (0.56) | CASP2DNM1FAAHNAAANOD1 | |
| SCHEMBL25453667 | 0.85 | FAAH (0.44) | FAAHNOD1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |