Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 10/20 | 0.49 |
| ▸ | PDE9A | O76083 | 4/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424223 | 1.00 | CLPP (0.49) | CLPPPDE9AFABP4GRIN2CSSTR3 | |
| SCHEMBL22424564 | 1.00 | CLPP (0.49) | CLPPPDE9AFABP4GRIN2CSSTR3 | |
| SCHEMBL22424704 | 0.87 | CLPP (0.45) | CLPPPDE9AFABP4 | |
| SCHEMBL22424333 | 0.84 | CLPP (0.54) | CLPPPDE9AHPGD | |
| SCHEMBL22423967 | 0.81 | P2RX7 (0.41) | HPGD | |
| SCHEMBL22424185 | 0.80 | MAPT (0.40) | GRIN2CHPGD | |
| SCHEMBL22424208 | 0.80 | MAPT (0.40) | GRIN2CHPGD | |
| SCHEMBL22423936 | 0.80 | MAPT (0.40) | GRIN2CHPGD | |
| SCHEMBL22424550 | 0.78 | CLPP (0.53) | CLPPPDE9AHPGD | |
| SCHEMBL22424585 | 0.77 | CLPP (0.52) | CLPPPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |