Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 18/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24275948 | 0.90 | P2RX7 (0.41) | P2RX7PGR | |
| SCHEMBL22423965 | 0.81 | P2RX7 (0.40) | P2RX7HPGDPGR | |
| SCHEMBL22424334 | 0.81 | HPGD (0.46) | HPGD | |
| SCHEMBL22424564 | 0.81 | CLPP (0.49) | HPGD | |
| SCHEMBL22424344 | 0.81 | CLPP (0.49) | HPGD | |
| SCHEMBL22424223 | 0.81 | CLPP (0.49) | HPGD | |
| SCHEMBL22410811 | 0.77 | P2RX7 (0.37) | P2RX7PGR | |
| SCHEMBL22410812 | 0.77 | P2RX7 (0.37) | P2RX7PGR | |
| SCHEMBL22423976 | 0.77 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL22424211 | 0.77 | P2RX7 (0.36) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |