Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CLPP | Q16740 | 18/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087175 | 0.80 | HPGD (1.00) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL22423998 | 0.75 | CLPP (0.60) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL22424056 | 0.67 | CLPP (0.56) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL3304711 | 0.66 | PNP (0.60) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL11760490 | 0.66 | PNP (0.60) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL2776453 | 0.65 | PNP (0.62) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL3053501 | 0.65 | SLC6A5 (0.58) | HPGDCLPP | |
| SCHEMBL721339 | 0.65 | SLC6A5 (0.58) | HPGDCLPP | |
| SCHEMBL14681363 | 0.64 | PARP14 (0.82) | HPGDPKML3MBTL1 | |
| SCHEMBL3433598 | 0.64 | PNP (0.68) | HPGDPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |