Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.95 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.95 |
| ▸ | CLPP | Q16740 | 17/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424688 | 0.80 | HPGD (0.67) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL9878904 | 0.79 | MAPT (0.75) | HPGDPKML3MBTL1 | |
| SCHEMBL14681363 | 0.77 | PARP14 (0.82) | HPGDPKML3MBTL1 | |
| SCHEMBL31087188 | 0.74 | HPGD (0.59) | HPGDPKML3MBTL1 | |
| SCHEMBL5190083 | 0.73 | MAPT (0.79) | HPGD | |
| SCHEMBL9878449 | 0.73 | MAPT (0.66) | HPGDPKML3MBTL1 | |
| SCHEMBL31087172 | 0.72 | HPGD (0.56) | HPGDPKML3MBTL1 | |
| SCHEMBL11760490 | 0.71 | PNP (0.60) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL3304711 | 0.71 | PNP (0.60) | HPGDPKML3MBTL1CLPP | |
| SCHEMBL22423945 | 0.71 | CLPP (0.58) | HPGDPKML3MBTL1CLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | INCYTE CORPORATION | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | MRGPRX1, MRGPRX4, MRGPRX2 | HPGD 831/4885PKM 3697/4885L3MBTL1 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.