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Sugi Predict / Compounds / Prostaglandin A1

Prostaglandin A1

Prostaglandin A1

SCHEMBL22425783

CCCCCC(O)/C=C/[C@H]1C=CC(=O)[C@H]1CCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 4/20 1.00
▸ NR4A2 P43354 3/20 1.00
▸ MEN1 O00255 2/20 0.72
▸ LMNA P02545 2/20 0.72
▸ HPGD P15428 2/20 0.72
▸ KMT2A Q03164 2/20 0.72
▸ HIF1A Q16665 2/20 0.72
▸ ALDH1A1 P00352 2/20 0.72
▸ POLB P06746 1/20 0.72
▸ NR4A1 P22736 1/20 0.72
▸ PTPN7 P35236 1/20 0.72
▸ SMN1; SMN2 Q16637 1/20 0.72
▸ PTGER4 P35408 5/20 0.64
▸ PTGER2 P43116 3/20 0.64
▸ PTGIR P43119 3/20 0.64
▸ TSHR P16473 2/20 0.64
▸ CYP3A4 P08684 1/20 0.64
▸ MAPK1 P28482 1/20 0.64
▸ ABCC3 O15438 1/20 0.64
▸ ABCC4 O15439 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prostaglandin A1 SCHEMBL6417551 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL11650631 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL17914205 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL8347686 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL3366007 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL14577651 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL23717317 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL6417548 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL13649323 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL8347690 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020182077-A1 USE OF GLI2 INHIBITOR AND METHOD FOR SCREENING COMPOUND INHIBITING GLI2 中国科学院动物研究所 2020-09-17 — — WO disclosed
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