Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 1.00 |
| ▸ | NR4A2 | P43354 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.64 |
| ▸ | PTGIR | P43119 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prostaglandin A1 SCHEMBL11650631 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL17914205 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL8347686 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL3366007 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL14577651 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL23717317 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL6417548 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL13649323 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL22425783 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD | |
| Prostaglandin A1 SCHEMBL8347690 | 1.00 | TRPA1 (1.00) | TRPA1NR4A2MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470251-B1 | LIQUID PROSTAGLANDIN COMPOSITION | GREEN CROSS CORP (JP) | 1996-02-07 | — | — | EP | claimed |
| EP-0470251-A1 | LIQUID PROSTAGLANDIN COMPOSITION | THE GREEN CROSS CORPORATION (JP) | 1992-02-12 | — | — | EP | claimed |
| US-4014989-A | Pharmaceutical aerosol compositions comprising putrescine prostaglandins | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | claimed |
| US-11077121-B2 | Inhibition of thymine DNA glycosylase in the treatment of cancer | INSTITUTE FOR CANCER RESEARCH (US) | 2021-08-03 | — | — | US | disclosed |
| US-20160199381-A1 | Inhibition of Thymine DNA Glycosylase in the Treatment of Cancer | INSTITUT DE GENETIQUE ET DE BIOLOGIE MOLECULAIRE ET CELLULAIRE (FR) | 2016-07-14 | — | — | US | disclosed |
| US-20050255161-A1 | Method for the long term stabilization of labile compounds at room temperature in pharmaceutical preparations containing water | MIDWEST RESEARCH LABORATORIES, LLC | 2005-11-17 | — | — | US | disclosed |
| EP-0470251-B1 | LIQUID PROSTAGLANDIN COMPOSITION | GREEN CROSS CORP (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-5182302-A | Infusion of mitogenic agent for enhanced proliferation of mammary tissue, increased milk production from cows | MONSANTO COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| US-5130300-A | Mitogenic effect on mammary glands | MONSANTO COMPANY (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0470251-A1 | LIQUID PROSTAGLANDIN COMPOSITION | THE GREEN CROSS CORPORATION (JP) | 1992-02-12 | — | — | EP | disclosed |
| US-5059586-A | Intermammary infusion of polypeptide growth factor in female ruminant | MONSANTO COMPANY (US) | 1991-10-22 | — | — | US | disclosed |
| US-4115545-A | Pharmaceutical composition containing prostadienoic acid for regulating gastric secretion | ALZA CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4055593-A | OXYTOCICS, ANTIULCER, DECONGESTANTS, ANTICLUMPING, MUSCLE RELAXANT, ANTISECRETORY, BLOOD PRESSURE, LIPOLYSIS | ALZA CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4014989-A | Pharmaceutical aerosol compositions comprising putrescine prostaglandins | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077121-B2 | Inhibition of thymine DNA glycosylase in the treatment of cancer | UNG, MPG, TYMP | TRPA1 4772/4885NR4A2 2676/4885MEN1 1230/4885 |
| US-20160199381-A1 | Inhibition of Thymine DNA Glycosylase in the Treatment of Cancer | UNG, MPG, TYMP | TRPA1 4772/4885NR4A2 2676/4885MEN1 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.