Prostaglandin A1

Prostaglandin A1

SCHEMBL6417548

CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 4/20 1.00
▸ NR4A2 P43354 3/20 1.00
▸ MEN1 O00255 2/20 0.72
▸ LMNA P02545 2/20 0.72
▸ HPGD P15428 2/20 0.72
▸ KMT2A Q03164 2/20 0.72
▸ HIF1A Q16665 2/20 0.72
▸ ALDH1A1 P00352 2/20 0.72
▸ POLB P06746 1/20 0.72
▸ NR4A1 P22736 1/20 0.72
▸ PTPN7 P35236 1/20 0.72
▸ SMN1; SMN2 Q16637 1/20 0.72
▸ PTGER4 P35408 5/20 0.64
▸ PTGER2 P43116 3/20 0.64
▸ PTGIR P43119 3/20 0.64
▸ TSHR P16473 2/20 0.64
▸ CYP3A4 P08684 1/20 0.64
▸ MAPK1 P28482 1/20 0.64
▸ ABCC3 O15438 1/20 0.64
▸ ABCC4 O15439 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prostaglandin A1 SCHEMBL6417551 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL11650631 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL17914205 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL8347686 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL3366007 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL14577651 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL23717317 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL13649323 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL22425783 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD
Prostaglandin A1 SCHEMBL8347690 1.00 TRPA1 (1.00) TRPA1NR4A2MEN1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119944436-B Multi-step ridge type laser structure and preparation method thereof 四川布鲁镭光科技有限公司 2026-05-15 — — CN claimed
CN-122038348-A Genome editing system for corynebacterium glutamicum 中国科学院分子植物科学卓越创新中心 2026-05-15 — — CN claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 — — US claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 — — US claimed
CN-119944436-A Multi-step ridge type laser structure and preparation method thereof 四川布鲁镭光科技有限公司 2025-05-06 — — CN claimed
US-20250120907-A1 Transmucosal Drug Delivery System Masiz, John J. (US) 2025-04-17 — — US claimed
CN-119788011-A Gain adjusting circuit of programmable gain amplifier and adjusting method thereof 慷智集成电路(上海)有限公司 2025-04-08 — — CN claimed
US-12246098-B2 Trans-epithelial membrane drug delivery system BioPhysics Pharma, Inc. (US) 2025-03-11 — — US claimed
CN-119584743-A Micro LED chip and manufacturing method thereof 北京字跳网络技术有限公司 2025-03-07 — — CN claimed
CN-119362427-A Forced power oscillation disturbance source positioning method based on KDE transfer entropy causal analysis 东北电力大学 2025-01-24 — — CN claimed
CN-113992171-B Receiver and automatic gain control method thereof 华南理工大学 2022-06-24 — — CN claimed
US-20220175701-A1 TREATMENT OF MAJOR DEPRESSIVE DISORDER AND SUICIDAL IDEATIONS THROUGH STIMULATION OF HIPPOCAMPAL NEUROGENESIS UTILIZING PLANT-BASED APPROACHES THERAPEUTIC SOLUTIONS INTERNATIONAL, INC. (US) 2022-06-09 — — US claimed
CN-110334458-B Structural seismic capacity assessment method considering influence of initial damage state 哈尔滨工业大学 2022-05-24 — — CN claimed
CN-114430276-A Universal synchronous acquisition analog front end for piezoelectric signals and voltage reference circuit thereof 哈尔滨理工大学 2022-05-03 — — CN claimed
CN-114300011-A SRAM (static random Access memory) construction method, device, storage medium and intelligent equipment 上海华力集成电路制造有限公司 2022-04-08 — — CN claimed
US-11279876-B2 Phosphor and light-emitting device using same DENKA COMPANY LIMITED (JP) 2022-03-22 — — US claimed
CN-111658628-B Application of GLI2 inhibitor and screening method of compound inhibiting GLI2 中国科学院动物研究所 2022-03-01 — — CN claimed
CN-113992171-A Receiver and automatic gain control method thereof 华南理工大学 2022-01-28 — — CN claimed
EP-0470251-B1 LIQUID PROSTAGLANDIN COMPOSITION GREEN CROSS CORP (JP) 1996-02-07 — — EP claimed
EP-0470251-A1 LIQUID PROSTAGLANDIN COMPOSITION THE GREEN CROSS CORPORATION (JP) 1992-02-12 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605345-B2 Transdermal drug delivery system FABP2, VEGFA, CUTA TRPA1 325/4885NR4A2 1088/4885MEN1 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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