Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | CLK2 | P49760 | 3/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | ROS1 | P08922 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748995 | 0.81 | DYRK3 (0.51) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL23057505 | 0.81 | EGFR (0.41) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL29503435 | 0.79 | SRC (0.50) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL13218401 | 0.79 | SRC (0.50) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL130592 | 0.79 | SRC (0.50) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL29201238 | 0.79 | DYRK1A (0.50) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL29503436 | 0.79 | SRC (0.50) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL21362196 | 0.75 | ATG7 (0.43) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL15471369 | 0.75 | SRC (0.58) | RPS6KB1CSNK1A1CSNK1DCLK2SLK | |
| SCHEMBL868744 | 0.75 | PIK3CD (0.51) | ADKDYRK3RPS6KB1CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208411-B2 | Compositions and methods for treating parasitic diseases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200291030-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291030-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | LIPA, LSS, LIPC | ADK 2654/4885DYRK3 3682/4885RPS6KB1 3438/4885 |
| US-11208411-B2 | Compositions and methods for treating parasitic diseases | LIPA, LSS, LIPC | ADK 2654/4885DYRK3 3682/4885RPS6KB1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.